Sunday, 19 June 2011

Relationship between penile fracture and Peyronie's

It is often suggested that peyronie's disease can be caused by penile injury, and that does appear to be the case. This can sometimes be seen in cases of untreated penile fracture. In this study, we see that treated (surgically) cases of penile fracture rarely result in cases of peyronie's disease.

Of course a fracture of the penis is a medical emergency. On the other end of the scale, many men do not report any kind of injury to the penis, but still go on to develop peyronie's disease. It may be that a minor injury has occured which has resulted in the condiiton developing. There are various theories about "trapped inflammation", genetic susceptibility and the like, but each case of the condition appears to be quite individual, so it's all but impossible to know what causes peyronie's in every instance.

Thursday, 16 June 2011

Quick News

- Dr Lue has started prescribing 800mg x 3 pentoxiflyne to some patients. It has been said that better results are seen faster (especially in those with calcificulation)

- Positive noises regarding the UK Xiaflex study are starting to come out. One guy on the peyronies forum stated that he'd gone from 30 degrees to 18 after one course of treatment. Early days yet though. Hopefully more updates will emerge.

- Andropenis have launched a peyronie's disease specific traction device. I would think that it's more the instructions / treatment plan that differs than the device itself, but its positive that traction continues to be recognised as a viable treatment option.

- I noticed a movie mention of peyronie's disease in a review for Twelve Thirty. The score on imdb isn't particularly impressive, so I doubt many people will see it. Still, it's good to see that this condition is getting mentions outside of clinical environments.

Thursday, 2 June 2011

Collagenase (Xiaflex) Trial UK Update


We have been given the opportunity to screen a further ten patients for the Collagenase trial and although we had patients to fill these slots, two have pulled out and so there are two spaces going.

We are screening our next 8 patients tomorrow (3rd June 2011) with a view to injecting the first cycle on the 10th of June 2011. If there are any peyronies patients who are still interested in the trial, the spaces will be allocated on a first come, first serve basis and if they are able to fulfil the basic criteria. We would not expect the peyronies patients to come for their screening tomorrow as this is quite short notice, but we would be looking at screening them on Tuesday 7th June 2011 in the evening in time for starting treatment on the 10th June should they fulfill the criteria.

Any potential participants should email me on

Many thanks for your continued support from your website.

With kind regards

Yours sincerely,

Mandi Kayes

Lead Clinical Nurse Practitioner to Mr David J Ralph