Sunday, 24 October 2010


Below is an overview of a typical approach to treating peyronie's disease.

Oral Treatments - Front Line Treatments

Pentoxifylline - A prescription medication. Pentoxifylline has been offered to peyronie's patients since 2002 by renowned peyronie's disease expert Dr Tom Lue (and others). It's a conservative treatment and only moderately effective, but studies exist to back it up.

Second Line Treatments

These treatments either have positive studies directly relating to peyronie's disease treatment (COQ10, ALC) or in theory may be useful in combination with front line treatments.

Coenzyme Q10 - A very recent study suggesting that Coenzyme Q10 may have a meaningful place in peyronie's disease oral therapy. Time will tell whether or not this is the case.

Acetyl L Carnitine - The linked text directs you to a positive acetyl-l-carnitine study from a few years back. Acetyl L Carnitine isn't exactly heavily researched for the treatment of peyronie's disease, but it can't hurt to try it.

PDE5 inhibitors inhibitors (Viagra, Cialis, Levitra --> Comparsion) and L-arginine - Pentoxifylline, L-Arginine and Viagra is sometimes known as the PAV cocktail. It has been prescribed by some of the top urologists in the states as a combination aiming to help combat peyronie's disease.

Other Treatments

These treatments I'd describe as 'general', in the sense that they have not been shown to help with peyronie's disease (often no studies have involved their use), but in theory they have help reduce inflammation, scarring and so on in other conditions. Hence, they may be of use.

Pycnogenol - When combined with L-arginine pycnogenol is known to promote and improve the quality of erections. It it sometimes known as Prelox. Multiple studies support its effectiveness in treating mild to moderate erectile dysfunction.

All of the following also have anti inflammatory and/or antifibrotic qualities: Taurine, Vitamin D, Curcumin, Resveratrol.

Note: It is recommended that oral treatment regimens are combined with a mechanical treatments such as Traction or Vacuum Therapy. Typically traction or vacuum therapy is tried for 6 months or so. If the improvement is not satisfactory to the patient, he may consider that it is worthwhile sticking with these treatments, or undergoing surgery. Surgery only takes place when the condition is stable (typically a year or so after onset). Not all cases of peyronie's disease follow typical timescales. A urologist will advise you on which path to take. Helpful communities such as the peyronie's forum, may also provide comfort and assistance to sufferers.

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